ICG Perfusion

Nipple Sparing Mastectomy Perfusion Assessment with the PDE-Neo

Sara Sturgis Free Flap Perfusion, Free Flaps, Hamamatsu PDE, ICG Fluorescence, ICG Perfusion, Microsurgery, Microvascular, PDE Videos, Plastic Surgery, Reconstructive Surgery, Surgical Videos

PDE-Neo Visualization for Nipple-sparing Mastectomy Procedure from Mitaka USA on Vimeo.


Post-Mastectomy PDE-neo Visualization

Eric Sturgis Hamamatsu PDE, ICG Perfusion, Microsurgery, Microvascular, PDE Videos, Plastic Surgery, Reconstructive Surgery, Surgical Videos

PDE Evaluation from Mitaka USA on Vimeo.


PDE neo Free Flap Evaluation

Sara Sturgis Anastomosis, Free Flap Perfusion, Free Flaps, Hamamatsu PDE, ICG Fluorescence, ICG Perfusion, Microsurgery, Microvascular, PDE Videos, Plastic Surgery, Reconstructive Surgery, Surgical Videos

PDE-NEO Free Flap Evaluation from Mitaka USA on Vimeo.


PDE neo Breast Reconstruction with Free Flap

Sara Sturgis Free Flap Perfusion, Free Flaps, Hamamatsu PDE, ICG Fluorescence, ICG Perfusion, Microsurgery, Microvascular, PDE Videos, Plastic Surgery, Reconstructive Surgery, Surgical Videos

PDE-NEO Evaluation of Free Flap from Mitaka USA on Vimeo.


PDE neo Chest Reconstruction

Sara Sturgis Hamamatsu PDE, ICG Fluorescence, ICG Perfusion, Microsurgery, PDE Videos, Plastic Surgery, Reconstructive Surgery, Surgical Videos

Hamamatsu PDE NEO: Chest Reconstruction from Mitaka USA on Vimeo.


VIDEO: PDE Breast Free Flap Evaluation

Sara Sturgis Free Flap Perfusion, Free Flaps, General and Transplant Surgery, Hamamatsu PDE, ICG Fluorescence, ICG Perfusion, PDE Videos, Plastic Surgery, Reconstructive Surgery, Surgical Videos

PDE Breast Flap Evaluation from Mitaka USA on Vimeo.


The Diagnostic and Intraoperative Use of NIR ICG in Perforator Flap Procedures: An Animal Study (2009)

Eric Sturgis Anastomosis, Basic Research, Free Flap Perfusion, Free Flaps, General and Transplant Surgery, Hamamatsu PDE, ICG Fluorescence, ICG Perfusion, Microsurgery, Plastic Surgery, Reconstructive Surgery

Image-Guided Perforator Flap Design Using Invisible Near-Infrared Light and Validation with X-Ray Angiography 

In this study, 22 pigs were injected with a bolus of indocyanine green (ICG) through a central venous line and observed with a near infrared (NIR) camera to identify dominant perforator flaps from the deep superior epigastric artery (DSEA). After the flap was identified and cut, it was given another ICG injection to confirm perfusion. In 8 of 22 of the pigs NIR ICG was confirmed with x-ray angiography. Researchers made a direct correlation between the results of the NIR ICG and x-ray angiography. This 2009 animal study “validated the clinical relevance of ICG fluorescence to tissue perfusion… the use of NIR wavelengths for fluorescence emission minimizes tissue autofluorescence and photo scatter, resulting in relatively high sensitivity” (Matsui et al 4).

Bibliographic information

Matsui, A., Lee, B. T., & Frangioni, J. V. (2009). Image-guided perforator flap design using invisible near-infrared light and validation with x-ray angiography. Annals of Plastic Surgery63(3), 327-330. Retrieved from www.ncbi.nlm.nih.gov/pmc/articles/PMC2756078

PubMed Full Article


Plastic Surgical Applications of ICG

Eric Sturgis Free Flap Perfusion, Free Flaps, General and Transplant Surgery, Hamamatsu PDE, ICG Fluorescence, ICG Perfusion, Microsurgery, Plastic Surgery, Reconstructive Surgery

Laser-induced fluorescence of indocyanine green: plastic surgical applications

This article explores the usefulness of ICG fluorescence in the evaluation of pedicle flaps, monitoring of free tissue transfer and replants, as well as the objective determination of burn depth. The authors found that in addition to normal assessment methods (clinical observation), ICG fluorescence provides invaluable information to the plastic surgeon for the developing an efficient surgery plan. For determining burn depth, the authors wrote that ICG made it possible to objectively differentiate burn wounds that require excision and grafting and those that do not. For pedicle flaps, the authors found that a 1999 paper published in the Annals of Plastic Surgery suggested that the information taken from ICG imaging leads to accurate predictions about flap survival.

Bibliographic information

Holm, C., Mayr, M., Tegeler, J., Becker, A., Pfieffer, U., & Muhlbauer, W. (2003). Laser-induced fluorescence of indocyanine green: plastic surgical applications. European Journal of Plastic Surgery26, 19-35. doi: 10.1007/s00238-003-0466-0

PubMed Full Article


Using ICG to Research how Ointments and Dressings can Effect Healing in Burn Wounds

Eric Sturgis Hamamatsu PDE, ICG Fluorescence, ICG Perfusion, Plastic Surgery, Reconstructive Surgery, Surgical Videos, Wound Management

The influence of dressings and ointments on the qualitative and quantitative evaluation of burn wounds by ICG video-angiography: an experimental setup

This was a study involving burn victims that utilized ICG fluorescence to determine whether or not certain dressings and ointments were preventing angiogenesis. Reserachers found that indeed certain dressings and ointments caused a significant decrease in perfusion.

Bibliographic information:

Haslik, W., Kamolz, L. P., Winter, W., Meissl, G., & Frey, M. (2003). The influence of dressings and ointments on the qualitative and quantitative evaluation of burn wounds by ICG video-angiography: an experimental setup. Journal of the International Society for Burn Injuries30, 232-235.

PubMed Abstract


ICG Fluorescence and the Prediction of Flap Necrosis

Eric Sturgis Anastomosis, Free Flap Perfusion, Free Flaps, General and Transplant Surgery, Hamamatsu PDE, ICG Fluorescence, ICG Perfusion, Microsurgery, Microvascular, Plastic Surgery, Reconstructive Surgery

Prediction of flap necrosis with laser induced indocyanine green fluorescence in a rat model.
In this study, German researchers from Rechts der Isar Hospital in Munich used a rat model and ICG fluorescence to determine what level of perfusion gave good indication of future flap necrosis. In areas that would become necrotic they found that the perfusion rate was less than 25% than that of the surrounding area.

Bibliographic information:

Giunta, R. E., Holzbach, T., Taskov, C., Holm, P. S., Brill, T., Busch, R., Gansbacher, B., & Biemer, E. (2005). Prediction of flap necrosis with laser induced indocyanine green fluorescence in a rat model. Department of Plastic and Reconstructive Surgery, Munchen, Germany.

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